An experimental pill cut hot flashes and improved sleep for women in menopause — without using hormones

An experimental pill that reduces hot flashes in women going through menopause has shown positive results in two trials. The pill, called elinzanetant, works by blocking brain chemicals responsible for hot flashes and night sweats. It is an alternative to hormone replacement therapy, which many doctors are hesitant to prescribe due to potential health risks. Another similar drug, fezolinetant, has already been approved. The new pills target a pathway in the brain that controls hot flashes by decreasing estrogen levels. The studies demonstrated a significant reduction in hot flashes for women taking elinzanetant compared to a placebo.